PFAS Toxicology and Risk Assessment - Revision history

Admin at 21:04, 11 February 2026

2026-02-11T21:04:17Z

Admin at 20:53, 11 February 2026

2026-02-11T20:53:55Z

Admin at 20:50, 11 February 2026

2026-02-11T20:50:22Z

Admin at 22:53, 23 January 2026

2026-01-23T22:53:40Z

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2025-12-31T17:54:05Z

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‎PFAS Exposure and Conceptual Site Models

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 *[[PFAS Sources]]
 *[[PFAS Transport and Fate]]
 '''Contributor(s):''' [[Jennifer Arblaster]], [[Dr. Jason Conder]], [[Dr. Jean Zodrow]] and [[Elizabeth Nichols]]
 '''Key Resource(s):'''

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 *[[PFAS Sources]]
 *[[PFAS Transport and Fate]]
 '''Contributor(s):''' [[Jennifer Arblaster]], [[Dr. Jason Conder]], [[Dr. Jean Zodrow]] and [[Elizabeth Nichols]]
 '''Key Resource(s):'''

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 *[[PFAS Transport and Fate]]
-'''Contributors:''' [[Jennifer Arblaster]], [[Dr. Jason Conder]], [[Dr. Jean Zodrow]] and [[Elizabeth Nichols]]
+'''Contributor(s):''' [[Jennifer Arblaster]], [[Dr. Jason Conder]], [[Dr. Jean Zodrow]] and [[Elizabeth Nichols]]
 '''Key Resource(s):'''

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 *[[Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS)]]
 *[[PFAS Sources]]
 *[[PFAS Transport and Fate]]

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 [https://www.atsdr.cdc.gov/pfas/health-studies/index.html Agency for Toxic Substances and Disease Registry (ATSDR) PFAS Health Studies]
-[https://soundcloud.com/arcadis-north-america/critical-data-for-assessing-the-marine-toxicity-and-bioaccumulation-of-pfas SERDP & ESTCP PFAS Research and Remediation Podcast : Critical Data for Assessing the Marine Toxicity and Bioaccumulation of PFAS]
+[https://soundcloud.com/arcadis-north-america/critical-data-for-assessing-the-marine-toxicity-and-bioaccumulation-of-pfas SERDP & ESTCP PFAS Research and Remediation Podcast: Critical Data for Assessing the Marine Toxicity and Bioaccumulation of PFAS]
-[https://soundcloud.com/arcadis-north-america/multi-generational-pfas-exposure SERDP & ESTCP PFAS Research and Remediation Podcast : Multi-Generational PFAS Exposure]
+[https://soundcloud.com/arcadis-north-america/multi-generational-pfas-exposure SERDP & ESTCP PFAS Research and Remediation Podcast: Multi-Generational PFAS Exposure]

← Older revision		Revision as of 17:53, 31 December 2025
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	[https://soundcloud.com/arcadis-north-america/critical-data-for-assessing-the-marine-toxicity-and-bioaccumulation-of-pfas SERDP & ESTCP PFAS Research and Remediation Podcast : Critical Data for Assessing the Marine Toxicity and Bioaccumulation of PFAS]		[https://soundcloud.com/arcadis-north-america/critical-data-for-assessing-the-marine-toxicity-and-bioaccumulation-of-pfas SERDP & ESTCP PFAS Research and Remediation Podcast : Critical Data for Assessing the Marine Toxicity and Bioaccumulation of PFAS]
		+
		+	[https://soundcloud.com/arcadis-north-america/multi-generational-pfas-exposure SERDP & ESTCP PFAS Research and Remediation Podcast : Multi-Generational PFAS Exposure]

← Older revision		Revision as of 17:50, 31 December 2025
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	==See Also==		==See Also==
	[https://www.atsdr.cdc.gov/pfas/health-studies/index.html Agency for Toxic Substances and Disease Registry (ATSDR) PFAS Health Studies]		[https://www.atsdr.cdc.gov/pfas/health-studies/index.html Agency for Toxic Substances and Disease Registry (ATSDR) PFAS Health Studies]
		+
		+	[https://soundcloud.com/arcadis-north-america/critical-data-for-assessing-the-marine-toxicity-and-bioaccumulation-of-pfas SERDP & ESTCP PFAS Research and Remediation Podcast : Critical Data for Assessing the Marine Toxicity and Bioaccumulation of PFAS]

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 This article provides a brief overview of the environmental toxicology and risk assessment of per- and polyfluoroalkyl substances (PFAS). The article’s main focus is on the environmental toxicology and risk assessment of PFAS derived from aqueous film-forming foam (AFFF).
-<onlyinclude>The use of [[Wikipedia: Firefighting foam | aqueous film-forming foam (AFFF)]] can release PFAS into the environment during fire training, an emergency response, or as a result of leaks or spills from AFFF systems. Following AFFF releases, perfluoroalkyl acids (PFAAs), particularly PFOS, PFOA, and PFHxS, tend to be the most commonly detected PFAS in environmental media. </onlyinclude>Due to their solubility, sorption, and bioaccumulation properties, perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl sulfonic acids (PFSAs) can be prevalent in a variety of environmental media, including groundwater, surface water, soil, sediment, biosolids, landfill leachate, plants, fish, invertebrates, and wildlife<ref>Lau, C., 2012. Perfluorinated Compounds. In: ''Molecular, Clinical and Environmental Toxicology, Volume 3: Environmental Toxicology'', A. Luch (Ed.), pp. 47-86. Springer Science and Business Media. [https://doi.org/10.1007/978-3-7643-8340-4_3 doi: 10.1007/978-3-7643-8340-4_3]</ref>.
+<onlyinclude>The use of [[Wikipedia: Firefighting foam | aqueous film-forming foam (AFFF)]] can release [[Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) | PFAS]] into the environment during fire training, an emergency response, or as a result of leaks or spills from AFFF systems. Following AFFF releases, perfluoroalkyl acids (PFAAs), particularly PFOS, PFOA, and PFHxS, tend to be the most commonly detected PFAS in environmental media. </onlyinclude>Due to their solubility, sorption, and bioaccumulation properties, perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkyl sulfonic acids (PFSAs) can be prevalent in a variety of environmental media, including groundwater, surface water, soil, sediment, biosolids, landfill leachate, plants, fish, invertebrates, and wildlife<ref>Lau, C., 2012. Perfluorinated Compounds. In: ''Molecular, Clinical and Environmental Toxicology, Volume 3: Environmental Toxicology'', A. Luch (Ed.), pp. 47-86. Springer Science and Business Media. [https://doi.org/10.1007/978-3-7643-8340-4_3 doi: 10.1007/978-3-7643-8340-4_3]</ref>.
 PFAS exhibit a range of physical and chemical properties, with the fate of the PFAAs, particularly the PFCAs and PFSAs, being the most studied PFAS. <onlyinclude>PFAAs are relatively water-soluble and mobile in the environment, are not volatile (i.e., they do not evaporate to the atmosphere readily</onlyinclude><ref>Field, J., Higgins, C., Deeb, R., Conder, J., 2017. FAQs Regarding PFASs Associated with AFFF Use at U.S. Military Sites. Environmental Security Technology Certification Program (ESTCP) Project ER-201574. [https://serdp-estcp.mil/resources/details/ccf87a8d-f8b2-4fce-bc4a-78c32091f896 Project Website]&nbsp; [[Media: FAQ_ER-201574.pdf | Report.pdf]]</ref><onlyinclude>) and can sorb to the organic carbon present in soil or sediment. </onlyinclude>PFAAs are more soluble and mobile compared to other persistent organic chemicals of concern documented at contaminated sites. <onlyinclude>PFAS can bioaccumulate in animals and plants, and persistent PFAS, such as PFCAs and PFSAs, do not undergo significant biodegradation or biotransformation once present in a biological system</onlyinclude><ref>Conder, J.M., Hoke, R.A., de Wolf, W., Russell, M.H., Buck, R.C., 2008. Are PFCAs Bioaccumulative? A Critical Review and Comparison with Regulatory Criteria and Persistent Lipophilic Compounds. Environmental Science and Technology, 42(4), pp. 995-1003. [https://doi.org/10.1021/es070895g doi: 10.1021/es070895g]</ref><onlyinclude>. </onlyinclude>